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In recent years, the research community has become increasingly concerned with issues involving the manipulation of images in scientific papers. Some of these alterations—involving images from experimental techniques such as microscopy, flow cytometry, and western blots—are inadvertent and may not change the conclusions of papers. But in rare cases, some are done deliberately to mislead…

In recent years, the research community has become increasingly concerned with issues involving the manipulation of images in scientific papers. Some of these alterations—involving images from experimental techniques such as microscopy, flow cytometry, and western blots—are inadvertent and may not change the conclusions of papers. But in rare cases, some are done deliberately to mislead…

Proofig screens images for duplication and other types of manipulation. It is similar to the iThenticate plagiarism detection software (which Science has been using for 7 years), but it works on images rather than text. Science has been piloting Proofig for several months with clear evidence that problematic figures can be detected prior to publication, so its use will…